At present, more than 100 different chemical species have been detected in interstellar space, primarily in giant gas clouds scattered throughout our Galaxy. The objectives of my research are to study these molecules and their chemistry via an interdisciplinary approach that involves both high resolution molecular spectroscopy in the laboratory and observational techniques of radio astronomy. The work primarily concerns (1) laboratory spectroscopy of potential interstellar molecules and (2) observational studies of these molecules using radio telescopes.