2024

Adams AC, Macy AM, Borden ES, Herrmann LM, Brambley CA, Ma T, Li X, Hughes A, Roe DJ, Mangold A, Buetow KH, Wilson MA, Baker BM, Hastings KT. Distinct sets of molecular characteristics define tumor-rejecting neoantigens. Preprint BioRxiv; 2024 Feb: 10.1101/2024.02.13.579546 (Full text)

2023

Macy AM, Herrmann LM, Adams AC, Hastings KT. MHC class II in the tumor microenvironment: functions of non-professional antigen presenting cells, Current Opinion in Immunology; 2023 Apr 30: 83:102330. PMID: 37130456 (Full text)

2022

Adams AC, Borden ES, Macy AM, Thomson N, Cui H, Gimbel MI, Wilson MA, Buetow KH, Roe DJ, DiCaudo DJ, Homsi J, Hastings KT; High GILT Expression Is Associated with Improved Survival in Metastatic Melanoma Patients Treated with Immune Checkpoint Inhibition. Cancers (Basel), 2022;14(9):2200. PMID: 35565329 (Full text)

Borden ES, Ghafoor S, Buetow KH, LaFleur B, Wilson MA, Hastings KT; NeoScore integrates characteristics of the neoantigen:MHC class I interactions and expression to accurately prioritize immunogenic neoantigens, Journal of Immunology, 2022; 208(7):1813-1827. PMID: 35304420

  • Selected as Top Read

Borden ES, Buetow KH, Wilson MA, Hastings KT; Cancer neoantigens: challenges and future directions for prediction, prioritization and validation. Frontiers in Oncology, 2022; 12:836821. PMID: 35311072 (Full text)

Adams AC, Macy AM, Kang P, Castro-Ochoa KF, Wijeratne EMK, Xu YM, Liu MX, Charos A, Bosenberg MW, Gunatilaka AAL, Sertil AR, Hastings KT; Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest. Translational Oncology, 2022; 15(1):101259. PMID: 34735896 (Full text)

2021

Borden ES, Adams AC, Buetow KH, Wilson MA, Bauman JE, Curiel-Lewandrowski C, Chow H-H S, LaFleur BJ, Hastings KT; Shared gene expression and immune pathway changes associated with progression from nevi to melanoma. Cancers, 2021, 14(1):3. PMID: 35008167 (Full text)

Adams AC, Macy AM, Saboda K, Dickinson SE, Glembocki DJ, Roe DJ, Hastings KT; Solar simulated light induces cutaneous squamous cell carcinoma in inbred mice: a clinically relevant model to investigate T cell responses. Journal of Investigative Dermatology, 2021; 141(12):2990-2993.e6. PMID: 34252399

2020

Rausch MP, Meador LR, Metzger TC, Li H, Qiu S, Anderson MS, Hastings KT; GILT in thymic epithelial cells facilitates central CD4 T cell tolerance to a tissue-restricted, melanoma-associated self antigen, Journal of Immunology, 2020; 204(11):2877-2886. PMID: 32269095 (Full text)

  • Featured on the cover of this issue (shown below) 

2019

Borden ES, Kang P, Natri HM, Phung TM, Wilson MA, Buetow KH, Hastings KT; Neoantigen fitness model predicts lower immune recognition of cutaneous squamous cell carcinomas than actinic keratoses. Frontiers in Immunology, 2019; 10:2799. PMID: 31849976 (Full text)

Buetow KH, Meador LR, Menon H, Lu YK, Brill J, Cui H, Roe DJ, DiCaudo DJ, Hastings KT; High GILT expression and an active and intact MHC class II antigen presentation pathway are associated with improved survival in melanoma, Journal of Immunology, 2019; 203(10):2577-2587. PMID: 31591149 (Full text)

Rausch MP, Hastings KT; Innate and adaptive immune responses to cancer; In textbook of Fundamentals of Cancer Prevention; Springer-Verlag, New York, NY; 2019; Alberts, DS, Hess, LM, eds.; 4th edition. (Full text)

Publications before 2019

2018

Meador LR, Hastings KT. Gamma-interferon-inducible lysosomal thiol reductase; In textbook of Encyclopedia of Signaling Molecules; Springer; New York, NY; 2018; Sangdun Choi, ed; 2nd edition. (Full text)

2017

Rausch MP, Hastings KT; Immune checkpoint inhibitors in the treatment of melanoma: from basic science to clinical application; In textbook of Cutaneous Melanoma: Etiology and Therapy; Codon Publications, Brisbane, Australia; 2017; Ward, WH, Farma, JM, eds. PMID: 29461774 (Full text)

Hastings KT, Elizalde D, Muppana L, Levine S, Kamel CM, Ingram W, Kirkpatrick JT, Hu C, Rausch MP, Gallitano AL; Nab2 maintains thymus cellularity with aging and stress, Molecular Immunology, 2017; 85:185-195. PMID: 28282643 (Full text)

2016

Nguyen J, Bernert R, In K, Kang P, Sebastiao N, Hu C, Hastings KT; Gamma-interferon-inducible lysosomal thiol reductase is upregulated in human melanoma, Melanoma Reseach; 2016; 26(2):125-37. PMID: 26930048 (Full text)

2015

Rausch MP, Hastings KT; Diverse cellular and organismal functions of the lysosomal thiol reductase GILT, Molecular Immunology; 2015; 68(2 Pt A):124-8. PMID: 26116226 (Full text)

Rausch MP, Hastings KT; An exhaustion-like phenotype constrains the activity of  CD4+ T cells specific for a self and melanoma antigen, PLoS One; 2015; 10(4):e0123332. PMID: 25875653 (Full text)

2014

Rausch MP, Hastings KT;  Innate and adaptive immune responses to cancer; pp 81-122; In textbook of Fundamentals of Cancer Prevention; Springer-Verlag, New York, NY; 2014; Alberts, DS, Hess, LM, eds.; 3rd edition. (Full text)

2013

Hastings KT, GILT: shaping the MHC class II-restricted peptidome and CD4+ T cell-mediated immunity, Frontiers in Immunology; 2013; 4:429. PMID: 24409178 (Full text)

Phipps-Yonas H, Cui H, Sebastiao N, Brunhoeber PS, Haddock E, Deymier MJ, Klapper W, Lybarger L, Roe DJ, Hastings KT; Low GILT expression is associated with poor survival in diffuse large B-cell lymphoma, Frontiers in Immunology; 2013; 4:425. PMID: 24409177 (Full text)

Phipps-Yonas H, Semik V, Hastings KT; GILT expression in B cells diminishes cathepsin S steady-state protein expression and activity, European Journal of Immunology; 2013; 43(1): 65-74. PMID: 23012103 (Full text)

2012

Rausch MP, Hastings KT; GILT modulates CD4+ T cell tolerance to the melanocyte differentiation antigen tyrosinase-related protein 1, Journal of Investigative Dermatology; 2012; 132(1):154-162. PMID: 21833020 (Full text)

  • Highlighted with a Commentary: Becker JC, Schrama D; Control of central and peripheral tolerance to melanocyte differentiation antigens by GILT, Journal of Investigative Dermatology; 2012; 132(1):15-17.

2011

Hastings KT, Cresswell P. Disulfide reduction in the endocytic pathway: immunological functions of gamma interferon–inducible lysosomal thiol reductase, Antioxidants & Redox Signaling; 2011; 15(3):657-68. PMID: 21506690 (Full text)

2010

Rausch MP, Irvine KR, Antony PA, Restifo NP, Cresswell P, Hastings KT; GILT accelerates autoimmunity to the melanoma antigen tyrosinase-related protein 1, Journal of Immunology; 2010; 185(5):2828-35. PMID: 20668223 (Full text)

Hastings KT, Glusac EJ, Wilson LD, Girardi M; Mycosis fungoides and Sézary syndrome: pathophysiology and pathology; In textbook of Lymphoid Neoplasms; Hodder Arnold, London, England; 2010; Magrath, I, ed.; 3rd edition. (Full text)

2008

Hastings KT; Innate and adaptive immune responses to cancer; In textbook of Fundamentals of Cancer Prevention; Springer-Verlag, New York, NY; 2008; Alberts, DS, Hess, LM, eds.; 2nd edition. (Full text)

2006

Hastings KT, Lackman, RL, Cresswell, P; Functional requirements for the lysosomal thiol reductase GILT in MHC class II-restricted antigen processing; Journal of Immunology; 2006; 177 (12):8569-8577. PMID: 17142755 (Full text)

2005

Taraszka KS; Erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis; pp 270-271; In textbook of Field Guide to Internal Medicine; Lippincott Williams and Wilkins, Philadelphia, PA; 2005; Smith, D, Sullivan, L, Hay, S, eds.

2004

Chavel S, Taraszka KS, Schaffer JV, Lazova R, Schechner JS; Calciphylaxis associated with acute, reversible renal failure in the setting of alcoholic cirrhosis; Journal of the American Academy of Dermatology; 2004; 50 (5):S125-S128. PMID: 15097947

Taraszka KS, Dover JS; Erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis; pp 893-895; In textbook of Conn’s Current Therapy; Saunders, Philadelphia, PA; 2004; Rakel, RE, Bope, ET, eds.

2003

Taraszka K, Girardi M; Treatment of cutaneous T cell lymphoma: advances in understanding disease behavior and implications for management; pp 1-26; Monograph published in Year Book of Dermatology and Dermatologic Surgery; Mosby, St. Louis, MO; 2003; Theirs, BH, Lang, PG eds.

  • Featured as the Special Focus Article on Clinical Dermatology for the Year Book annual review series

2000

Taraszka KS, Higgins JMG, Tan K, Mandelbrot DA, Wang JH, Brenner MB; Molecular basis of integrin αEβ7 recognition of E-cadherin; Journal of Experimental Medicine; 2000; 191 (9):1555-1567. PMID: 10790430 (Full text)

  • Featured on the cover of this issue (shown on right) 

1991

Taraszka KS, Chen E, Metzger T, Chance MR; Identification of structural markers in vitamin B12 and other corrinoid derivatives in solution using FTIR spectroscopy; Biochemistry; 1991; 30:1222-1227. PMID: 1991101